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Virginia Tech Hokies ACC |
| Year | Seed | Result | |
| 2024 | -- | -- | |
| 2023 | -- | -- | |
| 2022 | 11 | lost in 1st round | L Texas (6) |
| 2021 | 10 | lost in 1st round | L Florida (7) |
| 2020 | -- | -- | |
| 2019 | 4 | made the Sweet 16 | W St. Louis (13), W Liberty (12), L Duke (1) |
| 2018 | 8 | lost in 1st round | L Alabama (9) |
| 2017 | 9 | lost in 1st round | L Wisconsin (8) |
| 2016 | -- | -- | |
| 2015 | -- | -- | |
| 2014 | -- | -- | |
| 2013 | -- | -- | |
| 2012 | -- | -- | |
| 2011 | -- | -- | |
| 2010 | -- | -- | |
| 2009 | -- | -- | |
| 2008 | -- | -- | |
| 2007 | 5 | lost in 2nd round | W Illinois (12), L Southern Illinois (4) |
| 2006 | -- | -- |